Abstract

The present report developed from a preceding one [1] showing that the adult rat liver, ordinarily refractive to infection by Toolan's H-1 virus [2], could be rendered receptive by partial hepatectomy. This procedure results in a vigorous reparative activity, and the regenerating tissue thus becomes a favored target for a virus with an affinity for replicating cells. It seemed possible that Cysticercus fasciolaris, which is the larval form of the feline tapeworm Taenia taeniaeformis and induces an increase in mitotic activity throughout the liver of the rat, its natural host, might act in a similar manner in enhancing proliferation of the H-1 virus.

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