Abstract

Craniopagus conjoined twins are extraordinarily rare and present unique challenges to the multidisciplinary team. There is a paucity of literature on optimizing neuro-ophthalmologic evaluation in craniopagus twins. Herein, we present our enhanced neuro-ophthalmologic evaluation and management in 17-month-old male craniopagus twins, uniquely using handheld optical coherence tomography (OCT) plus portable slit-lamp biomicroscopy, indirect ophthalmoscopy and modified forced-choice preferential looking assessment. Staged surgical separation was supported by enhanced neuro-ophthalmologic evaluation, detailed radiology, three-dimensional printing and virtual reality simulation. This represents the fourth separation of craniopagus twins by our unit.

Highlights

  • Craniopagus conjoined twins are extraordinarily rare, occurring in one in 2.5 million births and representing only 2–6% of conjoined twins [1, 2]

  • A recent systematic review [3] outlined factors for surgical success, but there is a paucity of literature on optimizing ophthalmologic evaluation in craniopagus twins where highly specialized methods are required

  • optical coherence tomography (OCT) image acquisition is possible in craniopagus twins

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Summary

Introduction

Craniopagus conjoined twins are extraordinarily rare, occurring in one in 2.5 million births and representing only 2–6% of conjoined twins [1, 2]. Craniopagus conjoined twins are extraordinarily rare and present unique challenges to the multidisciplinary team. There is a paucity of literature on optimizing neuro-ophthalmologic evaluation in craniopagus twins.

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