Enhanced Imaging of Atherosclerotic Lesions in ApoE-deficient Mice using Nanotechnology

Gunter Almer

doi:10.3797/scipharm.cespt.8.pnm07

Abstract

first_page settings Order Article Reprints Font Type: Arial Georgia Verdana Font Size: Aa Aa Aa Line Spacing:    Column Width:    Background: Open AccessConference Report Enhanced Imaging of Atherosclerotic Lesions in ApoE-deficient Mice using Nanotechnology by G. ALMER 1,*, K. WERNIG 2, M. SABA-LEPEK 3, S. HAJ-YAHYA 1, J. KELLNER 4, J. RATTENBERGER 5, A. GRIES 4, R. PRASSL 3, A. ZIMMER 2 and H. MANGGE 1 1 Clinical Institute for Medical and Chemical Diagnosis, Medical University, Graz, Austria 2 Institute of Pharmaceutical Science, Department of Pharmaceutical Technology, University of Graz, Austria 3 Institute of Biophysics and Nanosystems Research, Austrian Academy of Sciences, Graz, Austria 4 Institute of Physiology, Medical University, Graz, Austria 5 Institute for Electron Microscopy and Fine Structure Research, Graz University of Technology, Austria * Author to whom correspondence should be addressed. Sci. Pharm. 2010, 78(3), 677; https://doi.org/10.3797/scipharm.cespt.8.PNM07 Received: 12 July 2010 / Accepted: 12 July 2010 / Published: 12 July 2010 Download Download PDF Versions Notes Abstract Atherosclerosis is the major cause of mortality in the western world today. [...] Share and Cite MDPI and ACS Style ALMER, G.; WERNIG, K.; SABA-LEPEK, M.; HAJ-YAHYA, S.; KELLNER, J.; RATTENBERGER, J.; GRIES, A.; PRASSL, R.; ZIMMER, A.; MANGGE, H. Enhanced Imaging of Atherosclerotic Lesions in ApoE-deficient Mice using Nanotechnology. Sci. Pharm. 2010, 78, 677. https://doi.org/10.3797/scipharm.cespt.8.PNM07 AMA Style ALMER G, WERNIG K, SABA-LEPEK M, HAJ-YAHYA S, KELLNER J, RATTENBERGER J, GRIES A, PRASSL R, ZIMMER A, MANGGE H. Enhanced Imaging of Atherosclerotic Lesions in ApoE-deficient Mice using Nanotechnology. Scientia Pharmaceutica. 2010; 78(3):677. https://doi.org/10.3797/scipharm.cespt.8.PNM07 Chicago/Turabian Style ALMER, G., K. WERNIG, M. SABA-LEPEK, S. HAJ-YAHYA, J. KELLNER, J. RATTENBERGER, A. GRIES, R. PRASSL, A. ZIMMER, and H. MANGGE. 2010. "Enhanced Imaging of Atherosclerotic Lesions in ApoE-deficient Mice using Nanotechnology" Scientia Pharmaceutica 78, no. 3: 677. https://doi.org/10.3797/scipharm.cespt.8.PNM07 Find Other Styles Article Metrics No No Article Access Statistics For more information on the journal statistics, click here. Multiple requests from the same IP address are counted as one view.

Highlights

Atherosclerosis is the major cause of mortality in the western world today
The main objective for the use of nanotechnology is to address prospects of imaging atherosclerotic (AS) plaques, which lead to clinical endpoints
The globular Adiponectin (gAd)-targeted NPs were investigated towards their potency to characterize critical scenarios within early and advanced AS-plaque lesions applying an AS-mouse model

Summary

Introduction

Atherosclerosis is the major cause of mortality in the western world today. The main objective for the use of nanotechnology is to address prospects of imaging atherosclerotic (AS) plaques, which lead to clinical endpoints. 1 Clinical Institute for Medical and Chemical Diagnosis, Medical University, Graz, Austria 2 Institute of Pharmaceutical Science, Department of Pharmaceutical Technology, University of Graz, Austria 3 Institute of Biophysics and Nanosystems Research, Austrian Academy of Sciences, Graz, Austria 4 Institute of Physiology, Medical University, Graz, Austria 5 Institute for Electron Microscopy and Fine Structure Research, Graz University of Technology, Austria Atherosclerosis is the major cause of mortality in the western world today.

Results

Conclusion