Enhanced Fuzzy Elephant Herding Optimization-Based OTSU Segmentation and Deep Learning for Alzheimer’s Disease Diagnosis

Abstract

Several neurological illnesses and diseased sites have been studied, along with the anatomical framework of the brain, using structural MRI (sMRI). It is critical to diagnose Alzheimer’s disease (AD) patients in a timely manner to implement preventative treatments. The segmentation of brain anatomy and categorization of AD have received increased attention since they can deliver good findings spanning a vast range of information. The first research gap considered in this work is the real-time efficiency of OTSU segmentation, which is not high, despite its simplicity and good accuracy. A second issue is that feature extraction could be automated by implementing deep learning techniques. To improve picture segmentation’s real-timeliness, enhanced fuzzy elephant herding optimization (EFEHO) was used for OTSU segmentation, and named EFEHO-OTSU. The main contribution of this work is twofold. One is utilizing EFEHO in the recommended technique to seek the optimal segmentation threshold for the OTSU method. Second, dual attention multi-instance deep learning network (DA-MIDL) is recommended for the timely diagnosis of AD and its prodromal phase, mild cognitive impairment (MCI). Tests show that this technique converges faster and takes less time than the classic OTSU approach without reducing segmentation performance. This study develops a valuable tool for quick picture segmentation with good real-time efficiency. Compared to numerous conventional techniques, the suggested study attains improved categorization performance regarding accuracy and transferability.