Enhanced control release of thyme essential oils from electrospun nanofiber/polyamidoamine dendritic polymer for antibacterial platforms

Abstract

The motive of the present investigation is to probe the role of polyamidoamine dendritic polymer (PAMAM) as a nano‐carrier function on the stepwise‐release rate of thyme oil (TEO) as natural extract with a superior antibacterial property. To represent quantitative and kinetic trends of release from nylon 6 electrospun fiber mats of TEO from mats, single‐sensor gas diagnosis device as an applicable diagnostic tool was tested in a distinct time sheet. All mats were characterized using scanning electron microscopy (SEM), Fourier‐transform infrared spectroscopy (FTIR), surface tension, contact angle, and antibacterial activity. As an outcome, PAMAM is major responsible for the pretending burst release due to the remarkable branches and cavities of PAMAM which encapsulate TEO. Noticeably, long‐term exposure of TEO was reached compared to the counterpart sample and a higher amount of PAMAM renders further functionality to protect guest molecules and not let them move easily in the atmosphere. It is realized that the essence release of mats with 2 and 10 wt% of PAMAM moieties last up to 9 and 12 days, respectively. Interestingly, all functionalized samples prevent the growth of Escherichia coli and Staphylococcus aureus bacteria and antibacterial value for samples with PAMAM surpassed 100% while decreased around 15 to 50% for mats without PAMAM over a 2‐week period. The results revealed that the functionalized samples were a promising fragrance delivery system with more effective antibacterial activity.