Abstract
The study describes the antibacterial and anticancer activities of a nanocomposite prepared by mixing zinc oxide and titanium dioxide nanoparticles. The particle mixtures were analyzed by X-ray diffraction, Field emission scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, and dynamic light scattering techniques. Thus, analyzed samples were subject to disc diffusion method at various concentrations to analyze their antibacterial activities against two Gram-positive and two Gram-negative bacteria. The same samples were then analyzed for their anticancer activities on four different cell lines. The results indicate a synergistic effect of the nanocomposite on both antibacterial and anticancer properties when compared to their individual counterparts.
Highlights
Nanomaterials are currently influencing a lot of our daily lives (Abbas et al 2009; Adeleye et al 2016)
The results indicate a synergistic effect of the nanocomposite on both antibacterial and anticancer properties when compared to their individual counterparts
The average crystallite sizes for these samples were analyzed by Debye–Scherrer’s formula [D = K 9 k/(b cos h)] and the results are indicated in Table 1. b is the full width half maximum (FWHM) of the XRD corresponding peaks, K is Debye–Scherer’s constant, D is crystallite size, k is wave length of the X-ray, and h is Bragg angle
Summary
Nanomaterials are currently influencing a lot of our daily lives (Abbas et al 2009; Adeleye et al 2016). Inorganic nanocomposites are a mixture of individually prepared nanoparticles combined at different concentrations (Ivanov et al 2003) as opposed doping (Rajendar et al 2013) or substitution (Ahmadipour et al 2012; Rajendar et al 2014a, b, 2016a). These particles would gallop the properties of both the nanoparticles simultaneously while retaining their individual characteristics. We have previously demonstrated potent antibacterial and anticancer activities of ZNPs and TNPs prepared by multiple synthesis routes
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