Abstract

English

Highlights

  • Ganoderma species belong to the division Basidiomycota, class Homobasidiomycetes, order Aphyllophorales and family Polyporaceae (Alexopoulos et al, 1996; Wasser and Weis, 1999a)

  • The structures and molecular formulae of the eight pure compounds are shown on Table 1

  • Based on the literature available to us, this is the first report on the isolation, structural elucidation and bioactivity of compounds from the fruiting bodies of G. zonatum

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Summary

Introduction

Ganoderma species belong to the division Basidiomycota, class Homobasidiomycetes, order Aphyllophorales and family Polyporaceae (Alexopoulos et al, 1996; Wasser and Weis, 1999a). The bioactive compounds from them have been implicated for their high antioxidant, immune-regulatory and hypoglycemic activities They have been known for their antihydrogenic, antitumor, antihepatotoxic, antinocieptic, immunodulatory, cardiovascular, antibacterial and antiviral values (Chang and Buswell, 1996; Chang and Mshigeni, 2001). Basidiomycetes, called macromycetes, are among the many diverse organisms and are a major source of biologically active natural products (Liu, 2004). They provide a rich variety of active secondary metabolites (Turner, 1971). Quite a wide range of substances from higher basidiomycetes belonging to different classes of chemical compounds have been described and their biological properties evaluated (Lorenzen and Anke, 1998; Mizuno, 1999)

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