Abstract
INTRODUCTION AND OBJECTIVES: Extended spectrum beta lactamase (ESBL) producing Klebsiella spp have emerged as an important pathogen due to their high resistance against most of the antibiotics. Their detection and antibiotic resistance pattern is required for proper management of cases. In this study we report the prevalence and antibiotic resistance of such Klebsiella isolates. METHODS: A total of 100 clinical isolates of Klebsiella from different clinical samples were tested for ESBL production by double disc approximation test and CLSI phenotypic method. Antibiotic susceptibility of all the Klebsiella isolates were performed by Kirby-Bauer disc diffusion test. RESULTS: of 100 Klebsiella isolates 53 showed ESBL production. All ESBL producers were resistant to beta lactam antibiotics. Antibiotic resistance among ESBL producing strains was high as compared to non ESBL producing strains. INTERPRETATION & CONCLUSION: In the present study a large number of Klebsiella spp. isolated were found to be ESBL producers. Continuing monitoring of ESBL production and antimicrobial susceptibility testing is essential to avoid treatment failure.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
