English

Abstract

BACKGROUND: One of the scoring systems in Pediatric Intensive Care is the PRISM III (PAEDITRIC RISK OF MORTALITY III) which is an updated version of PRISM. Study was done at time point 72 hrs of initiation of therapy as well in a view that it will better prognosticate the outcome. AIMS: 1. To find out PRISM III within 1st 12 hours of admission and at 72-84 hours of admission, 2. To evaluate any correlation between PRISM III and mortality, 4.To find out correlation between individual components of PRISM III and mortality DESIGN: A prospective cross-sectional study from 1 st June 2011 —31 st December 2013. Data was collected for 81 patients. METHODS AND MATERIAL: Variables used in the study were: Systolic BP, Heart rate, Temperature, Mental status, Pupillary reaction, Acidosis, pH, Total CO2, PaCO2, PaO2, Glucose, Potassium, BUN, Creatinine, WBC count, Platelet count, PT/aPTT. A detailed entry of various parameters included in the scoring system was made in the first 12 hours and thereafter 72-84 hours. The most abnormal value recorded. STATISTICAL ANALYSIS: All the data collected analyzed using STATA 8 after entering in excel sheet. Based on the clinical and laboratory data , PRISM III score was calculated. Categorical variables were compared with Chi-Square test. Calibration was assessed using Hosmer Lemeshow's goodness of fit test. CONCLUSION: Overall mortality rate was 27%. Among all the variables of PRISM III Systolic blood pressure, Heart rate, pupils, platelets, PT/APTT had statistical significance with mortality at both 0-12 and 72-84 hours. Temperature, GCS, BUN and creatinine showed statistical significance at 72-84 hours. Mortality was high with the as the scores increased in Systolic blood pressure, Heart rate, Temperature, GCS, BUN, Creatinine, WBC, PT/APTT at both 12 hours and 72 hours. Study showed significant relationship between PRISM III score and outcome. p value at 12 hours was 0.00961 which was significant and p value at 72-84 hours was 0.0000 which was extremely significant which suggested that mortality increased as the PRISM score increased and PRISM III score at 72-84 hours has depicted it better.