Abstract
This study was done at Christian Medical College and Hospital, Ludhiana for the period of 5 years from January 2006 to December 2010 in the Department of Microbiology. A total of 306 endoscopic gastric biopsy specimens were collected from the suspected cases of the peptic ulcer and were subjected to rapid urease test for Helicobacter pylori. This test has high sensitivity and cent percent specificity. The prevalence was determined to be 09.48% and male: female ratio was determined to be 68.97:31.03. INTRODUCTION: Helicobacter pylori is a common cause of peptic ulcer. It is gram negative, microaerophilic and motile organism with multiple polar flagella. It associated with 90% of duodenal ulcer and 80% of gastric ulcer¹.H.pylori is also associated with gastric adenocarcinoma. H. pylori infection is mainly acquired through the faeco oral route. Water has been shown to be a source of H. pylori infection by Kleinet al².A study from Bombay reported that H. pylori is present in the dental plaques of 98% patients with dyspepsia³.
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