Abstract
BACKGROUND The association between orofacial cleft and parental age is evident. This study focuses on paternal age playing a vital role in the birth of children with orofacial clefts. We wanted to assess the role of paternal age as a factor in the development of congenital anomalies in this study. METHODS A case control study was performed on 1000 cases and 250 controls in Mangalore. The parents were interviewed regarding their age at the time of conception. RESULTS 46.4 % of fathers of the cleft children belonged to 30 - 34 years of age group and 25 % belonged to 25 - 29 years of age group at the time of conception. In the control group, 38 % belonged to 30 - 34 years of age group and 24.8 % belonged to 25 - 29 years of age group. CONCLUSIONS Paternal age in the age group of 30 - 34 years has significant contribution in the birth of orofacial children with cleft deformities. KEY WORDS Orofacial cleft, Paternal Age, Congenital anomalies
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