Abstract
Context- Pelvic masses are common in women of all age groups and their accurate diagnosis poses a clinical challenge because of atypical and non specific presentation. The combination approach of exploratory laparotomy and histopathological examination remains the corner stone for management. CA 125, a biomarker has been evaluated in several studies as a surrogate tool in these cases. OBJECTIVES: To determine the diagnostic value of CA 125 in pelvic mass and to know its sensitivity and specificity in ovarian cancers. MATERIAL AND METHODS - 80 patients suspected of pelvic mass at JSS Hospital, Mysore subjected to clinical examination, CA 125 detection and laparotomy followed by histopathological correlation. RESULTS: CA 125 levels were seen to be more in large fibroids. High levels were recorded in extensive adenomyosis and endometrial carcinoma stage1A onwards. Sensitivity and specificity in post-menopausal women was 100% for malignant ovarian tumors. CONCLUSION -CA 125 estimation can be used as an adjunct tool in the evaluation of pelvic mass and is a highly useful assay in the diagnosis of ovarian cancers in the post-menopausal women.
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