Abstract
INTRODUCTION: Pseudomonas aeruginosa is the most common gram negative bacteria associated with nosocomial infections. In recent years, a considerable increase in the prevalence and multidrug resistance (MDR) P. aeruginosa has been noticed with high morbidity and mortality. The present study was conducted to find out the current antimicrobial susceptibility pattern of P. aeruginosa isolates obtained from clinical samples at our hospital. MATERIALS AND METHODS: Pseudomonas aeruginosa isolated from various clinical specimens during March 2013 to February 2014 were included in the study. Isolates were identified by conventional tests and antibiotic susceptibility was determined by disc diffusion method according to CLSI guidelines. RESULTS: A total of 159 Pseudomonas aeruginosa isolates were included in this study. Majority of isolates was found in pus followed by urine. Highest susceptibility was shown towards imipenem followed by amikacin and least susceptibility was shown towards cephalosporins. Multi-drug resistance was shown by 21isolates tested. CONCLUSION: P. aeruginosa showed higher rate of resistance towards commonly used antibiotics which may be due to indiscriminate prescription patterns. To prevent the selection and spread of the resistant bacteria, it is critically important to have strict antibiotic policies.
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