Abstract
Methicillin resistant Staphylococcus aureus (MRSA) strains emerged soon after the introduction of methicillin into clinical practice. In addition to being a nosocomial pathogen, MRSA has become a community pathogen. This study reports the prevalence and antibiotic susceptibility pattern of MRSA in tertiary care hospital in central India. MATERIAL AND METHODS: A total of 1042 clinical specimens were collected and strains identified using conventional microbiological methods. Subsequently the antibiotic sensitivity test was performed for the confirmed MRSA isolates using cefoxitin disc diffusion method. RESULTS: Out of 109 strains of S. aureus isolated, 70(64.22%) were found to be methicillin resistant. Amongst all MRSA, 65(92.85%) were resistant to penicillin, oxacillin and gentamicin, 40(57.14%) were resistant to erythromycin, 3(4.28%) clindamycin resistant, 54(77.14%) tobramycin and 60(85.71%) amikacin resistant. However, all the MRSA strains were sensitive to vancomycin. CONCLUSION: The determination of prevalence and antibiotic sensitivity pattern of MRSA will help the treating clinicians effectively and preventing irrational use of antibiotics.
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