Abstract
Different bacterial strains were isolated from soil, water and rotten fruit samples, and biochemically characterized as Shigella, Pseudomonas, Escherichia coli, Klebsiella andProteus. Unhygienic environment (for example, contaminated food, water and air) are the most common habitats of these pathogens. Mostly, all are involved in endemic breakouts causing urinary tract and gastro-intestinal infections. The antibacterial activity of four concentrations of natural crude extracts of medicinal plants namely Allium sativum(garlic), Nigella sativa (black cumin), Trigonella foenum-graecum (fenugreek), Ficus carica (fig), Azadirachta indica (Indian lilac) and honey was determined against a total of ten isolated organisms by well plate method. Test organisms were found to be more sensitive to aqueous extract of bulb of A. sativum, seeds of Nigella sativa and honey. The antibacterial activity of crude extract was comparable with ciprofloxacin and ceftriaxone, commonly used antibiotics for the treatment of infections in adults and children, respectively. It was observed from the studies that most of the test strains were resistant to the antibiotics used especially against ceftriaxone. Due to the emergence of drug resistant microorganisms, it is a need to search out more effective antimicrobial agents to cure the disease. Our studies suggest that aqueous crude extract of medicinally important plants and honey could be the alternative of the antibiotic to cure the diseases. Key words: Ceftriaxone, Ciprofloxacin, Nigella sativa, Shigella, Proteus.
Highlights
Each year millions of people get sick due to the contaminated food, air and water
The antibacterial activity of four concentrations of natural crude extracts of medicinal plants namely Allium sativum, Nigella sativa, Trigonella foenum-graecum, Ficus carica, Azadirachta indica (Indian lilac) and honey was determined against a total of ten isolated organisms by well plate method
The antibacterial activity of crude extract was comparable with ciprofloxacin and ceftriaxone, commonly used antibiotics for the treatment of infections in adults and children, respectively
Summary
Each year millions of people get sick due to the contaminated food, air and water. Pathogenic bacteria are the most common cause of illness. Around 1 billion people lack access to clean water and 2.5 billion have no access to basic sanitation. Common edibles available at local market are not properly cooked and kept in unhygienic conditions are major source of community acquired infections. Most of the people living in undeveloped areas live a life worst than that of animals. Their continued uncivilized existence is because Of their lack of awareness. Problems related to Abbreviations: MR, Methyl red; VP, Voges–Proskauer; TSI, triple sugar iron
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