Abstract
Traditional Chinese medicine (TCM), with its multi-target effects, is gaining more and more attention all over the world due to its specific theory and long historical clinical practice. But the absence of an objective and accurate inspection system is frequently cited as one of the major hurdles for its modernization and globalization. Benefiting from modern molecular biology and polymerase chain reaction (PCR) techniques, DNA markers have become one of the most reliable methods for identification and authentication of Chinese medicinal materials. This paper reviewed the recent progress of DNA markers, including PCR-based markers, hybridization-based markers, sequenced-based markers, and DNA microarray in the authentication of TCM. Key words: DNA marker, Traditional Chinese medicine (TCM), polymerase chain peaction (PCR).
Highlights
Traditional Chinese medicine (TCM) is an integral part of Chinese culture
Due to its long history of clinical use, reliable therapeutic efficacy, unique treatments, and systemic theories, TCM is getting increasing global attention; an increasing variety of natural bioactive compounds have been developed from TCM by many big, worldwide pharmaceutical companies to meet the contemporary trend of "back to nature" (Shaw et al, 2002)
DNA markers for TCM identification are less affected by age, physiological conditions, environmental factors, as well as harvest, storage and processing methods (Jiang et al, 2010)
Summary
Traditional Chinese medicine (TCM), with its multi-target effects, is gaining more and more attention all over the world due to its specific theory and long historical clinical practice. The absence of an objective and accurate inspection system is frequently cited as one of the major hurdles for its modernization and globalization. Benefiting from modern molecular biology and polymerase chain reaction (PCR) techniques, DNA markers have become one of the most reliable methods for identification and authentication of Chinese medicinal materials. This paper reviewed the recent progress of DNA markers, including PCR-based markers, hybridization-based markers, sequencedbased markers, and DNA microarray in the authentication of TCM
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
