Abstract

Chonglou is a well known traditional Chinese medicine for anti-cancer and traumatic injuries. The major sources of Chonglou are from genus Paris. The present investigation aimed to determine contents of active steroidal saponins in Paris plants collected from different locations of Southwest China. The results showed that polyphyllin I and polyphyllin VII could be detected in almost all samples. However, polyphyllin II and polyphyllin VI were not detected in the research. The results indicated that besides Paris polyphylla var. yunnanensis and P.polyphylla var. chinensis, used as medicine traditionally, other Paris species in Southwest China also have medicinal value. Ranges of bioactive compounds in P. polyphylla var. yunnanensis from different parts of the plants were wide. Coefficient of variation of polyphyllin I, polyphyllin II, polyphyllin VII, and total steroidal saponins were 53.4132, 43.9341, 88.2673, and 60.9082%, respectively. Varieties of compounds type and contents in Paris plants would be related to habitats.   Key words: Paris genus, polyphyllin, variation, high performance liquid chromatography (HPLC), Southwest China.

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