English

Abstract

60 patients of ASA undergoing upper limb surgeries were randomly assigned into two groups, Group BM (midazolam) and Group B (Bupivacaine) Surgery was done under supraclavicular approach of brachial plexus blockade. The Patients in Group BM received 30ml of 0.375% bupivacaine 5μ/kg midazolam and In group B received 30 ml of 0.375% of bupivacaine. Parameters observed were time of onset of sensory block and motor block, duration of motor blockade, duration of sensory block analgesic, duration of analgesia, sedation score, Haemodynamic and side effects. Study shows that On addition of midazolam to local anaesthetic solution there is difference between the onset of sensory block and onset of motor blockade to bupivacaine 1. On addition of midazolam to local anaesthetic solution significantly prolongs the duration of analgesia in 15-18 hours compared to bupivacaine group which is 8-16 hours. 2. Addition of midazolam to local anaesthetic solution increases the duration of motor blockade by 7-9 hours compared to bupivacaine which is 5-7 hours. 3. On addition of midazolam to local anaesthetic solution increases the duration of sensory block 15 hours compared to bupivacaine which is 5-9 hours. CONCLUSION: The addition of midazolam to local anaesthetic solution in supraclavicular approach to brachial plexus, a) Produces significantly faster onset of sensory & motor blockade. b) Prolongs the duration of sensory & motor blockade and duration of analgesia.