English

Rodrigues Aquino Samille,Torequl Islam Muhammad,Silva Geronço Maurycyo,Cardoso Melo Roberta,Leonardo Mendes Barros Hugo,Pinheiro Da Costa Marcília,Do Ó Pessoa Claudia,Dos Santos Rizzo Marcia,De Cássia Evangelista De Oliveira Fátima

doi:10.5897/jmpr2019.6872

Abstract

Adenanthera pavonina, an Asian native leguminous, is a well known highly used plant in traditional medicine. Such broad herbal medicine applications motivated several researchers to study its chemical composition, mainly of its leaves, seeds, and barks, besides the pharmacological effects aiming to demonstrate scientific evidence of its empirical uses. Most studies have been conducted with plant derivatives, and more recent studies have focused on isolated compounds. The phytochemical screening revealed various secondary metabolites with diverse biological effects, including flavonoids, alkaloids, saponins, tannins, steroids, triterpenoids, polyphenols, anthraquinones, coumarins, glycosides and polysaccharides. Experimental studies of this plant have shown numerous pharmacological activities such as antidiarrheal, anti-inflammatory, antinociceptive, antioxidant, antimicrobial, anticancer, and others. Advances in the studies of phytochemistry and biological activity on this plant species over the last years led to the increasing interest of researchers in the protection of inventions focusing on its cosmetic, pharmaceutical and food applicability. This review summarizes the tremendous therapeutic and technological potential of A. pavonina that should be explored, opening new perspectives for future researches and the development of new products. Key words: Febaceae, herbal medicine, leguminosae, plant extracts, toxicity.  

Highlights

Medicinal plants have traditionally been used in almost all cultures as a relevant therapeutic resource
These findings demonstrate the antinociceptive activity of this extract which may be associated with its chemical compounds and support the traditional use of this plant in the treatment of different painful conditions
It was possible to verify the range of knowledge related to the A. pavonina species

Summary

INTRODUCTION

Medicinal plants have traditionally been used in almost all cultures as a relevant therapeutic resource. Based on the traditional knowledge of the use of parts of this plant, several pharmacological effects of derivatives have been demonstrated, such as antinociceptive activity of leaf ethanol extract (Moniruzzaman et al, 2015), cytoprotective and antiinflammatory activity of seed extract (Koodalingam et al, 2015); antihyperglycemic and hypolipidemic effect of the aqueous extract of seeds (Pandhare et al, 2012a); antimicrobial and antioxidant activity of bark extracts (Ara et al, 2010b); antifungal activity relates to antimicrobial peptides present in seeds (Soares et al, 2012), among others Several studies on this species have helped to understand the toxicity and supported its traditional use. This broader approach will be valuable in assessing the scope of scientific studies and the technological potential of this species

METHODS

Findings

CONCLUSION