Abstract
Hepatitis D is the important complication in cirrhotic patients. Diagnosis of hepatitis D is based on detection of HBSAg and HDV Ab titer determination. The present research was performed on a number of cirrhotic patients with the aim to assess the prevalence of hepatitis D and B. In present study all the cirrhotic patients who were referred to Gastroenterology and Endoscopy ward of Imam Khomeini hospital during a period of 18 months were included. The level of anti HDV Ab, anti HBS Ab and HBS Ag were determined by method of ELISA (Pishtaz Teb). In this study 60 cirrhotic patients were evaluated. 16 patients were HBS Ag positive with mean age of 51.9 years, and from this group, 13 patients were anti HBC positive with mean age of 53.23 years and from this group, 8 patients were HDV Ab positive with mean age of 49 years. Hepatitis D remains as one of the problems in developing countries. By timely screening of cirrhotic patients for HDV, patients could undergo additional treatments. Key words: Liver cirrhosis, hepatitis D, hepatitis B, HBS Ag, HBC Ab, HDV Ab.
Highlights
Million patients in the worldwide are affected by chronic hepatitis B, especially in developing countries
There was no significant correlation between age and HBS Ag positive in cirrhotic patients (P value = 0.936)
There was no significant correlation between sex and HDV Ab positive cases among cirrhotic patients (P value = 1)
Summary
Million patients in the worldwide are affected by chronic hepatitis B, especially in developing countries. Patients with chronic hepatitis B might be asymptomatic while carrying the hepatitis virus (HBS Ag positive) (Tsatsralt-Od et al, 2005; Mandell et al, 2000). 15 million people in the world have chronic hepatitis D. Hepatitis D or Delta virus is a small round RNA virus which is dependent on hepatitis B virus. This virus cannot live or replicate unless with the envelop of hepatitis B virus and Similar to healthy carriers of hepatitis B , healthy carriers of hepatitis D exist too.(Farci et al, 2004; Mandell et al, 20004). The present study is implemented on a number of cirrhotic patients with the aim to assess the prevalence of hepatitis D and B in this group
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