Abstract

Misoprostol, a synthetic PGE₁, analogue may be used for induction of labour. It is a preliminary study to evaluate the efficacy and safety of intravaginal insertion of misoprostol 50ugm tablet for induction of labour. A total of 110 consecutive cases of singleton term pregnancy with cephalic presentation having Bishops cervical score ≤ 4 were included. Cases of CPD, placenta praevia, previous uterine scars and twin conceptions were excluded. Ninety-six women had vaginal delivery and 14 cases had caesarean deliveries. Average induction delivery interval was 10.8 ± 4.8 hours. Apgar score of newborn at 1 minute was 8.86 ± 0.735. Induction of labour with single dose of 50 µgm of misoprostol vaginally is effective as other inducing agents with no obvious side-effects to both mothers and newborns

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