Abstract

A new series of 1,2,4-triazole derivatives (4a-j, 6a-j) have been synthesized by the 1,3-dipolar cycloaddition of a suitable nitrilimines 2 to pyruvaldehyde (2-oxopropanal) hydrazones having (COPh, COOMe, COOEt, Me/Me and Me/Ph) 3 and 5. Both analytical and spectroscopical data of all the synthesized compounds are in full agreement with the proposed structures. The microbial features of the synthesized compounds were studied by a known method.

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