Abstract
Cordia globosa is used to treat gastrointestinal diseases in San Rafael Coxcatlan, Puebla, Mexico; however, its medicinal properties have not been investigated. This study reports the chemical composition and the antimicrobial effect of C. globosa essential oil. The essential oil of aerial parts was obtained by steam distillation and 25 compounds were identified by gas chromatography-mass spectrometry (GC-MS). The major constituent was α-pinene (38.4%). Antimicrobial activities were tested on 6 bacterial and 9 fungi strains. The most sensitive strain was Vibrio cholera (minimum inhibitory concentration [MIC], 0.060 mg/ml). These results show the chemical composition and biological properties of essential oil of C. globosa. The results validate the medicinal use of C. globosa. Key words: Cordia globosa, Boraginaceae, antimicrobial activity, essential oil.
Highlights
Cordia globosa (Jacq.) Kunth (Boraginaceae) is a shrub that grows in tropical lands of America
Constituents (25), comprising 92.0% of the oil from aerial parts of C. globosa were characterized by gas chromatography-mass spectrometry (GC-MS) (Table 1). α-Pinene was the major monoterpene constituent in the essential oil comprising 38.4% of the total
These compounds determine the biological properties of the oils (Bakkali et al, 2008). This is the first report of the composition of the essential oils of C. globosa collected in México
Summary
Cordia globosa (Jacq.) Kunth (Boraginaceae) is a shrub that grows in tropical lands of America. This plant is known as “blood herb” in San Rafael Coxcatlán, Puebla, Mexico and the infusion of aerial parts is used for diseases like skin fungal infections, gastrointestinal and throat of posible infectious origin as well as for its antitussive, astringent, hemostatic and tonic (Hernández et al, 2003). Phytochemical studies of C. globosa include the isolation of meroterpenoid benzoquinones with cytotoxic activity against several cancer cell lines (Menezes et al, 2005).
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