Abstract
The aim of this study was to determine the correlation between glycated hemoglobin and blood sugar levels in diabetic subjects carried out in Abidjan. This cross-sectional study included 100 patients with diabetes monitored, for three months, for whom glycated blood glucose and hemoglobin were performed, this after informed consent of the patients. Pearson and Spearman correlation tests were used, at the 5% threshold. The patients with normal HbA1C and normal blood glucose accounted for 55.34 and 32%, respectively. A sedentary lifestyle and body mass index > 25 kg/m² were associated with a significant increase in the risk of increased blood glucose and HbA1C. The presence of a complication was associated with a 3.06-fold higher risk of high glycated hemoglobin (p= 0.0073), while blood glucose was not significantly associated with the onset of complications. Glycated hemoglobin was significantly correlated with blood glucose with a correlation coefficient of 0.4412 (p 0.0001). In multivariate analysis, hyperglycemia was significantly associated with alcohol consumption and non-compliance with antidiabetic treatment. Poor compliance was significantly associated with increased glycated hemoglobin (>7%) and tobacco consumption. The glycated hemoglobin was highly correlated with blood sugar, and was found to be a better predictor of diabetes complications than glycemia. Key words: Diabetes mellitus, glycated hemoglobin, blood sugar, Abidjan, Cote d’Ivoire.
Highlights
The complications of diabetes are influenced by the duration of diabetes and by the average level of chronic glycemia which is measured most reliably with glycated hemoglobin (HbA1C) assay (Lenters-Westra and Slingerland, 2008; ADA, 2009)
Alcohol consumption was observed in 44% of patients and we recorded 19% of patients consuming tobacco
Our results showed that lack of physical activity increased the risk of obesity, hyperglycemia and HbA1C by more than 7% (Table 3)
Summary
The complications of diabetes are influenced by the duration of diabetes and by the average level of chronic glycemia which is measured most reliably with glycated hemoglobin (HbA1C) assay (Lenters-Westra and Slingerland, 2008; ADA, 2009). Dietary measures, most of which are associated with drug treatments, are essential for a good patient balance (Colette and Monnier, 2010) The aim of these measures is to reduce insulin resistance, glycemic, lipid and blood pressure disturbances, and to prevent the disease from worsening (Verma et al, 2006; Colette and Monnier, 2010). The simple determination of blood glucose levels on a periodic basis at the time of checkups prior to visits to the medical practitioner cannot provide a correct picture of the long-term control of diabetic disease. To overcome this deficit, biochemical markers, including HbA1C, are used to help assess the glycemic balance of patients (Shubrook, 2010)
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