English

Abstract

BACKGROUND: A single centre study was planned to assess prevalence of H. pylori infection in patients suffering from acid peptic disorders, in order to find out the burden of the disease. OBJECTIVES: To assess the prevalence of H. pylori infection in patients suffering from acid peptic disorders. METHODOLOGY: A total of 100 subjects, suspected clinically as cases of acid peptic disorder, were subjected to upper gastro intestinal endoscopy. Two biopsies were taken and sent for rapid urease test and histopathological examination. STATISTICAL ANALYSIS: The data obtained was coded and entered in Microsoft Excel Spreadsheet. The categorical data was expressed as rates, ratios and percentages and comparison was done using chi-square test. RESULTS: Total of 100 subjects was studied, of which 66 were males and 34 were females. Rapid urease test was positive for H. pylori infection in 40 %(n=40) of the patients and histopathological report revealed 49% (n=49) of the patients with H. pylori infection. Based on both the diagnostic modalities of which either one may be positive (rapid urease test or histopathological examination) the H. pyloric prevalence in acid peptic disorder patients was found to be 59%. CONCLUSIONS: Present study showed high prevalence of H. pylori in patients with acid peptic disorders. The infection with H pylori was not associated with age, sex and place of residence.