English

Abstract

OBJECTIVES: Prevalence rates of coronary artery disease are reported to be very high in Asian Indians. Traditional risk factors alone fail to explain the high rates of coronary disease in Indians. Acute phase reactants C-reactive protein in Indian subjects with unstable angina were evaluated and compare them with suitable control to test the hypothesis that a relationship exists between acute phase reactants and unstable angina. METHODOLOGY: 50 cases unstable angina and 50 suitable cases enrolled for the study. Unstable angina had significantly increased level of CRP compare to control group (p=0.01098).RESULTS: Statistically significant difference was found between case and control group in TLC (p=0.0037) and ESR (p=0.0368), TLC and ESR being more in case group as compare to control group. C- reactive protein was significantly correlated with TLC and ESR in case group and TLC and ESR in control group. C reactive protein, TLC and ESR in case group while no correlation was observed with any variable in control group. CONCLUSION: The present study concludes that a relationship exists between acute phase reactant studied and unstable angina.