Abstract
Hypovolemia is a state of decreased blood volume. Both crystalloids and colloids can be used but may influence coagulation beyond hemodilution. Hydroxy ethyl starch (HES) is colloids that are routinely used as intravascular volume substitutes. This prospective Randomized double blinded study was conducted in 60 patients to demonstrate the equivalence of two different molecular weight of HES in the initial management of Hypovolemia. Tetra starch (Voluven) HES130/0.4 produced excellent effect and makes it an advantage especially in hypovolemic patients because of Adequate Volume Effect Reduced tissue elimination, improved safety profile, Increased Renal elimination.
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