Abstract

In the recent past, the importance of freshwater algae has grown enormously due to their antibiotic activity against certain species of bacteria known for several disease states like endocarditis, external otitis, skin rash, etc. Also, there is a growing concern among the immunocompromised individuals that they may be susceptible to antibiotics and anti-fungal resistant infections resulting in increased fatality rates. Hence, in this investigation, extraction of potentially bioactive compounds from natural resources like freshwater algae was performed along with the evaluation of the antimicrobial activities of these extracts against some opportunistic bacteria like Staphylococcus aureus, Escherichia coli, Staphylococcus xylosus and Pseudomonas aeruginosa using well diffusion method. The data showed a statistically significant (P < 0.05) antibacterial activity of the organic extracts (0.1 g/ml) obtained from freshwater algae against multi-drug resistant S. aureus and S. xylosus strains as compared to the control. Our data reinforce the importance of bioactive compounds from fresh algae as potential antimicrobial agents, and they could act as an alternative to conventional antibiotics. Key words: Freshwater algae, Organic extracts, Antimicrobial activity, Opportunistic bacteria, Methicillin Resistant Streptococcus, Natural Antibiotics.

Highlights

  • Algae are plant-like organisms with no roots, stem, or leaves, having photosynthesis process for converting light energy into chemical energy

  • The inhibition zones of each extracted sample were measured against four different types of bacteria such as E. coli, S. aureus, S. xylosus, and P. aeruginosa

  • It was demonstrated that the ethanol extract of freshwater algae using Soxhlet extraction method had a statistically significant antibacterial effect against S. aureus and S. xylosus (Figure 4, P

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Summary

Introduction

Algae are plant-like organisms with no roots, stem, or leaves, having photosynthesis process for converting light energy into chemical energy. They are found in freshwater ponds, lakes with few exceptions in slow running water (Naik et al, 2012; Mei et al, 2021). The Oedogonium spp. has numerous advantages, for example, Oedogonium capillare was notably used in traditional medicine for the treatment of various human ailments such as dysentery, diarrhea, thrush on tongues of babies, wound healing, and as an antiseptic agent for various skin diseases (Perez-Gutierrez, 2006) It could act as feed for many organisms such as frogs, fish as well as for biomass applications in a freshwater ecosystems (Lawton et al, 2014)

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