Abstract
In order to test the role of platelet activation in the talar osteochondral disease, the mean platelet volume (MPV) in patients undergoing treatment of talar osteochondral disease was evaluated. White blood cell count and highly sensitive C-reactive protein were evaluated in 50 patients with osteochondral defect of talus. Disease activity was assessed according to American Orthopedic Foot and Ankle Society scoring. Additionally, visual analog scale for the pain assessment was used for the study. Biochemical parameters, rehabilitation parameters, and MPV levels were compared with each other at the admission and 3 weeks after surgery. MPV was significantly lower in patients with osteochondral lesions of talus after treatment as compared to admission levels. MPV and C-reactive protein levels decreased together. American orthopedic foot ankle score of the patients were increased after surgery. Visual analog scale decreased suggestive levels. It was proposed that MPV provides a useful marker in activity of inflammatory osteochondral disease. The aim of this study is to define the effect of platelet activation in talar osteochondral disease. Key words: Talus, osteochondral lesion, platelet volume (MPV), biomarker.
Highlights
Urinary incontinence is a common complaint causing suffering and embarrassment as well as significant costs to women and societies around the world (Department of Health, Modernising Health and Social Services, 19992002)
The patients were asked to fill in the International Consultation on Incontinence modular Questionnaire Short Form (ICIQ-SF), which is a validated measure of overactive bladder syndrome and health-related quality of life (Abrams et al, 2006)
A total of 61 patients were suitable for a day case surgical procedure
Summary
Urinary incontinence is a common complaint causing suffering and embarrassment as well as significant costs to women and societies around the world (Department of Health, Modernising Health and Social Services, 19992002). Tension-free vaginal tape (TVT) procedure has been the standard minimally invasive treatment for SUI since 1995, when it was first described by (Ulmsten and Pteros, 1995; Delorme 2001), cused the 'outside-in' technique of a transobturator route for suburethral tape placement, the transobturator tape (TOT) procedure (Delorme, 2001). This technique reduced the risk of bladder perforation and injuries to the bowels and large vessels compared with TVT. Despite its improved safety profile and excellent cure rates, the procedure still involves passing needles through the Variable Age Parity Pre-op cough stress test (CST)+ve USI Pure SUI MUI
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