Abstract
Amputation of lower extremity followed by use of leg prosthesis is very common. However, malignancy arising in the amputation stump is extremely rare. We are reporting such a case in a 52-year-old man. Review of the English literature reveals only five additional cases occurring in men with an average age of 65 years and after a mean lag period of 40 years between the amputation and development of a low-grade squamous cell carcinoma.
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