English

Abstract

CONTEXT: AIMS: Comparison between intravenous iron sucrose & oral ferrous fumarate in chronic anaemia due to chronic haemorrhoids. SETTINGS AND DESIGN: METHODS AND MATERIAL: This study was conducted on 30 patients with chronic anaemia with Hb from 4.4 – 8 gm/dl. The patients were randomized into two groups. Group 1 consisted of 15 patients who received 300-600 mg of intravenous iron sucrose every alternate day for 3 days. Group2 consisted of 15 patients & were given 300 mg of ferrous fumarate orally daily for 14 days. Statistical analysis used: RESULTS: After 14 days in group1 the Hb increased by 2.8 gm/dl in comparison to 1 gm/dl in group 2. CONCLUSIONS: The results show that use of intravenous iron sucrose increases Hb level more rapidly than oral therapy in chronic anaemic patients of haemorrhoids without any side effects. KEY-WORDS: Chronic anaemia, iron sucrose, ferrous fumarate. KEY MESSAGES: INTRODUCTION: The prevalence of chronic anaemia in haemorrhoid patients is quite common because of chronic bleeding. This leads to morbidity such as lethargy, tiredness, dizziness. Anaemia is usually due to chronic and excessive bleeding in haemorrhoid patients comparing to haemoglobin formation by body. Blood transfusion is often required for severe cases or oral iron medication is added for increasing haemoglobin along with measures to stop further bleeding. Oral iron can cause some side effects like constipation, which is not good for haemorrhoids, nausea and gastric irritation which effects compliance. Blood transfusion gives quick results but have higher chances of infections like hepatitis B & C, HIV. Due to this intravenous iron therapy has been considered an alternative as now available iron sucrose is very safe and hardly have any side effects. Hence the main aim of this study is to compare effectiveness of intravenous iron sucrose versus oral ferrous fumarate in anaemic patients. Subjects and Methods: The study was randomized & performed at Dept. of surgery in S G T medical college, Gurgaon. The study included 30 patients in the age group of 35-65 years with Hb in range of 4.4-8 gm. The patients were randomized into two groups as per there Hb level. After approval of ethical committee of college and taking consent from patients 15 patients were selected in group 1 and 15 patients were included in group 2. Treatments: Group 1 received 300-600 mg of intravenous iron in two or three divided doses given every alternative day for 3 days. The dose was calculated by formula as Total iron dose in mg = 2.4 x wt x deficit