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OBJECTIVES: Characterization of solid masses and assignment of levels of suspicion for being malignant on color and spectral Doppler and to co-relate the findings with histopathological features. MATERIAL AND METHODS: Sixty four patients with breast masses were evaluated with duplex and color Doppler ultrasound. Presence or absence of color flow, number of vessels, their situation and spectral Doppler analysis were performed. Comparison of color Doppler analysis with histopathological findings was done. RESULTS: Color signals were more commonly found in malignant (88%) than benign lesions (38%). Malignant lesions showed more number of vessels as compared to benign. Both central and peripheral vascularity was noted in 14 out of 16 malignant masses and in none of the benign masses. Spectral Doppler analysis did not prove to be helpful in differentiating benign from malignant lesions. CONCLUSION: Color Doppler is helpful in assigning a higher level of suspicion to a lesion for being malignant. Spectral Doppler analysis did not contribute to the differentiation between malignant and benign breast tumors. Therefore despite increased examination time, as an adjunct to B mode sonography, color Doppler evaluation is useful in solid breast masses, especially of indeterminate nature.