English

Abstract

First AIDS case was reported in 1986. In India, 71.4% of all HIV estimated to be women with an accompanying increase in vertical transmission & pediatric HIV(1).The HIV epidemic has penetrated into the general population(2). The transmission may occur late in pregnancy & during delivery(3) & through breast milk(4). AIMS: To find out the prevalence of HIV in pregnancy and its effect on perinatal outcome. METHODS: A prospective study was conducted in Loni Maharashtra during July 2001– June2003. All the women registered in the antenatal clinic were subjected to Rapid test :comb Aids – RSkit, HIV EIA Comb Test and CAPILLUS Test after counseling and written informed consent according to the PPTCT programme. Positive result of all three tests were taken as confirmed positive result. All Sero–positive women received tab Nevirapine 200 mg single dose in active phase of labour. Babies of all sero-positive women received syrup Nevirapine 2ml/kg body weight within 72 hrs of birth. Statistical analysis was done using chi-square test. RESULTS: The prevalence rate of HIV in present study was found to be 1.85%. The relationship of HIV seropositivity with preterm labour (16% VS 7% ,Z=1.97,P<0.05) was statistically significant. The difference in mean birth weight of HIV positive versus HIV negative women was 176 , which is significant statistically. CONCLUSION: The HIV prevalence in the present study was found to be 1.85% . Considering the low risk behavior & rural based study population, it appears to be quite high.We can conclude from this study that pregnant women are not at risk of adverse maternal & perinatal outcome. INTRODUCTION: First AIDS case was reported in 1986. In India, 71.4% of all HIV estimated to be women with an accompanying increase in vertical transmission & pediatric HIV (1).The HIV epidemic has penetrated into the general population (2). The transmission may occur late in pregnancy & during delivery (3) & through breast milk (4). AIMS: o To find out the prevalence of HIV in pregnancy. o To study the effect of HIV on perinatal outcome. o To provide comprehensive counselling support & to control the vertical transmission of HIV infection. METHODS: A prospective study was conducted at -Pravara Medical College, loni Maharashtra during July 2001– June2003.Counselling & written informed consent through prevention of parent to child transmission (PPTCT) programme was done. A sample of 2cc blood was collected in a plain bulb & subjected for HIV testing as per PPTCT protocol-