Abstract
Aim: Honey and Garcinia kola have long been used separately by the traditional medical practitioners as remedies for cough and other ailments. Recently, a combination of both as a remedy for cough is common. This work was intended to see the effect of this synergy on the kidney. Methods: Twenty five Wistar albino rats weighing 180±10g were grouped into 5 (A, B, C, D, E) of 5 rats each. They were fed twice daily for 14 days with a mixture of G. kola and honey: 0.16g/kg + 0.5ml, 0.20g/kg + 0.5ml, 0.24g/kg + 0.5ml, 0.28g/kg + 0.5ml and normal feeds respectively. The rats were sacrificed on the 15th day and blood and kidneys were taken for biochemistry and histology respectively. Results: Sodium, potassium, chloride, bicarbonate, urea, creatinine, as well as the histology of the kidney of the test rats were not significantly different from the control rats. Conclusion: Oral intake of one nut Garcinia kola along with about 5 ml honey twice daily for 14 days has no adverse effect on the kidney. Key words: Honey, Garcinia kola, Liver, Medicinal plant
Highlights
Honey is a sweet substance obtained from bees and has long been used as a remedy for certain ailments such as gastric disturbances, ulcers and asthma
It has been used as an antibiotic and as an antiseptic (Grotte, 1998). It promotes wound healing and circulatory system (Pand, 2014). It has been used for the treatment of chronic rhinosinusitis (Philip, 2014) and for sore throat and cough (Chris, 2014) as well as an ointment for rashes and burns (Vanghn, 2001)
MATERIALS AND METHODS Preparation of Garcinia kola Five nuts of G. kola were obtained from Owo, Ondo State, Nigeria
Summary
Honey is a sweet substance obtained from bees and has long been used as a remedy for certain ailments such as gastric disturbances, ulcers and asthma. It has been used as an antibiotic and as an antiseptic (Grotte, 1998). It promotes wound healing and circulatory system (Pand, 2014). Iwu et al, (1990) regarded the plant as a wonder plant because every part of it from the bark, leaves, root, wood to the seed has medicinal value. Adesanya et al, (2007) confirmed its use as a spermatogenic agent in AVWIORO ET AL
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