Abstract
OBJECTIVES: To study the clinical profile of ABM and analyse the differences in clinical presentation among young infant, toddler, compared to school going children. And to find out the bacteriological profile and sensitivity pattern of ABM. MATERIALS AND METHODS: The present study is a prospective non-randomized single arm study. Children with the diagnosis of ABM admitted to the department of Pediatrics Govt. General Hospital, Kurnool from January 2013 to October 2013 are included in the study. Clinical details of all patients were recorded CSF was analysed by routine biochemical methods, and microbiological studies on special media. The children were managed as per the standard protocols. RESULTS: In a study period of 1 year During the study period 74 children (1.5% of all admissions) satisfied the criteria of ABM in early childhood;. The incidence of Acute Bacterial Meningitis was 1.45% of total Pediatric admissions. Of the 74 cases 25 died. Mortality rate was 33.79%.mortality observed was more in less than one year of age. Chief presentation was high fever, refusal of feeds, altered sensorium and seizures. The final etiological diagnosis (as per LAT and/or cultures) were 32 cases are positive for culture and sensitivity of ABM and Biochemically and Cell count wise 74 cases are positive for ABM. CSF has grown pneumococci in 8 (25%) cases, Coagulase positive Staph. Aureus in 3 (9.38%) cases, Coagulase negative Staph. Aureus in 3(15.63%) cases, Nesseria Meningitides in 3 (9.38%), Klebsiella in 4 (12.50%) cases, E coli, Enterococci and Pseudomonous in 9 (28.13%) The outcome in the present study with respect to death is 33.78% and 45.95% of patients Survived with complications, 20.27% of patients survived without complications. CONCLUSION: The incidence and Mortality were significantly high in low socio economic group. The incidence and mortality was high in lesser age group. Mortality is very high with high CSF protein and low sugar levels. Pneumococci and coagulase negative staphylococci are predominant causes of morbidity and mortality associated with ABM.
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