Abstract
English
Highlights
Toxins produced by filamentous fungi are called mycotoxins
Patulin (Figure A), is an unsaturated heterocyclic lactone produced by certain fungal species of Penicillium, Aspergillus and Byssochlamys growing on fruit[4]
Histological Results In light microscopic examination the renal cortex of the control group was characterized by the presence of renal corpuscles, proximal and distal convoluted tubules (PCT&DCT)
Summary
Toxins produced by filamentous fungi are called mycotoxins. This term, by general consensus, is used almost exclusively for fungi associated with food products and animal feed, excluding toxins produced by mushrooms[1]. Mycotoxins are secondary metabolites, with no apparent function in the normal metabolism of fungi. They are produced mainly, out exclusively, when the fungus reaches maturity[2]. Animal tissues affected by PAT administration included kidney and intestine[6,7]. The sub-acute administration of patulin has been mainly studied in rats, where it was shown to induce weight loss, gastric and intestinal changes and alterations in renal function[9]. Repetitive doses lead to signs of neurotoxicity (tremors, convulsions) as well as an inhibition of several enzymes (ATPase) in the intestine[10], and the brain, in particular, with consequences in terms of lipid
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