Abstract
OBJECTIVES : To evaluate efficacy of sublingual misoprostol versus oxytocin drip for induction and augmentation of labor in prelabor rupture of membranes. METHODS : The study included 200 pregnant women with singleton term pregnancy with cephalic presentation, leaking per vaginum and no contraindications to vaginal delivery. They were randomised in two groups, 100 in sublingual misoprostol group and 100 for oxytocin drip group. Induction delivery interval, mode of delivery, incidence of operative interference and maternal and fetal outcome were noted and analysed. RESULTS : Mean induction delivery interval was 8 hrs in misoprostol group and 15 hrs in oxytocin group. Mode of delivery was vaginal in 99% in misoprostol group but 80% in oxytocin group. Sublingual misoprostol was associated with less meconium passage (1%) compared to 20% in oxytocin group. CONCLUSION : Sublingual misoprostol is a good alternative to oxytocin drip for induction and augmentation of labour in women with PROM.
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