Abstract
Obesity and uncontrolled weight gains is associated with changes in anthropometric variables and hematological parameters. Therefore, this study aims to assess anthropometric variables and hematological parameters among people with obesity. This study was carried out at Central Hospital, Sapele, General Hospital, Oghara and Biomed Diagnostic Centre, Sapele in Southern Nigeria. 415 subjects with age between 18 and 65 years were enrolled for this study including 312 obese experimental subjects (comprising of 111 males and 201 females) and 103 non-obese normal control subjects (comprising 40 males and 63 females). 5.0 ml of venous blood was collected from all subjects into EDTA container and full blood count was determined using Sysmex XN330 automated hematology analyzer. Anthropometric variable of all subjects were measured using standard methods. Monocyte count of obese and non-obese individuals was 6.40±0.23×109/L and 5.14±0.18×109/L when Neutrophil-lymphocyte ratio (NLR) of obese and non-obese people was 1.57±0.21 and 1.18±0.05, respectively. Waist height ratio (WHtR) of obese people was 27.56±0.30 inch/m while WHtR of non-obese/normal people was 17.83±0.22 inch/m. Obese and non-obese people had waist hip ratio of 0.92±0.01 and 0.90±0.01 respectively. Hip circumference (HC) of obese subject was 49.56±0.48 inch and HC of non-obese people was 33.37±0.53 inch. Nevertheless, body mass index (BMI) and mean height of obese people were 36.82±0.55 kg/m2 and 1.66±0.01 m while BMI of non-obese people were 20.43±0.29 kg/m2. Of all hematological parameters, only monocyte and NLR values were higher in people with obesity than in non-obese people and the value of all measured anthropometric variables were higher in obese subject than in non-obese people. Key words: Anthropometric variables, hematological parameters, Sapele.
Highlights
IntroductionObesity is a medical condition in which excess fat has accumulated in our body to the level that produces
There was no significant difference in hematological parameters of obese and non-obese people and no difference in values of hemoglobin, packed cell volume and red blood cell count compared with normal weight subject, this implies that weight gains has no effect on hematopoietic processes and iron metabolism, this result is in agreement with an earlier report that overweight and obese subjects does not have lower hemoglobin and red blood cell count and obesity occur when excess energy intake exceeds energy usage, which does not considerably affect iron metabolism to cause anemia in adult obese subjects (Revelo et al, 2014)
Obese subjects had significantly higher Neutrophil-Lymphocytes Ratio (NLR) value when compared with normal non-obese people and this implies that, obesity and excessive weight gain increases Neutrophillymphocyte ratio (NLR) due to inflammatory processes that is common in obesity
Summary
Obesity is a medical condition in which excess fat has accumulated in our body to the level that produces. A combination of too much calories intake and sedentary life style are the major causes of obesity, which results in the formation of excess adipose tissue either in the visceral or in the subcutaneous cavity (Lau et al, 2007). Small number of obesity is due to hereditary, medical reasons, decreased variability in ambient temperature and interference with lipid metabolism (Bleich et al, 2008). The main treatment for obesity consists of diet control and physical exercise (Lau et al, 2007; LeFevre and Michael, 2014)
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