English

Abstract

OBJECTIVE: Study of placental morphological changes in intrauterine growth restricted babies. MATERIAL & METHODS: The Study was carried out at Mahatma Gandhi Medical College & Hospital, Jaipur, from January 2011 to January 2012. The placentae were collected from 50 cases of mothers of normal for date babies &50 cases of mothers of IUGR babies. Placental changes studied in both the groups, grossly and histopathologically. RESULTS: The placentae were collected from fifty mothers of normal for date babies & fifty mothers of growth restricted babies. It was observed that mean placental & fetal weights were 385 + 15gm in IUGR as compared to control group 500 + 15 gm Total gross & microscopic pathology in each group were 46% & 94% respectively in IUGR group as compared to 8% each in control groups. Mean fetal weight was low in IUGR group in relation to socioeconomic status, smoking & various disease factors. CONCLUSION: Gross morphology and histopathology of placentae were studied. Gross changes were developmental anomalies, placenta extrachorialis 2% & placenta bipartite 2%. Mean placental diameter in IUGR group was found to be less 15.58 cms as compared to 18.48cms in control group. Tesselation and subchorionic fibrosis was present in 70% & 76% in IUGR group which was found to be less as compared to 90% & 94%in control group1.Calcification, infarction and retroplacental haematoma were present in 54%, 56% & 26% in IUGR which was found more in comparison to 24% &12%in control group. It was concluded