Abstract
Chlamydia trachomatis is a major causative agent of sexually transmitted disease (STD), which can damage a woman’s reproductive organs. The prevalence of Chlamydia trachomatis infection was investigated among 200 pregnant women attending antenatal clinics in three hospitals located within Kaduna metropolis, North-Central, Nigeria. Enzyme linked immunosorbent assay technique was performed to detect chlamydia antibodies. The overall prevalence of C. trachomatis in the population studied was 9.5% (19/200). The highest percentage of prevalence rate, 6.5% (13/200), was seen in women belonging to the age group of 25 or less; this corresponds to women in their late teens and early twenties, and was also the most sexually active age group. Polygamy and low income status were also associated with higher infection rates. The commonest symptom recorded for the respondents that tested positive to Chlamydia infection was found to be vaginal irritation (27.8%), followed by vaginal discharge (25.9%); other symptoms observed were dysuria (14.8%) and lower back pain (9.3%). 18.5% of respondents had a past history of sexually transmitted diseases (STDs). The distribution of women that tested positive for C. trachomatis antigen within the hospitals investigated showed that 11%, (11/100) were from Yusuf Dantsoho Memorial Hospital, with a similar number, 11.66% (7/60), from Kawo General Hospital, while Shehu Mohammed Kangiwa Medical Centre was seen to have only 2.5% (1/40) positive cases. C. trachomatis infection is largely underdiagnosed in the population, therefore specific preventive and intervention strategies for Chlamydia infection should be developed and targeted among the sexually active general population. Key words: Chlamydia trachomatis, pregnant women, antenatal clinics, seroprevalence, ELISA.
Highlights
Chlamydia is a common sexually transmitted disease caused by the bacterium Chlamydia trachomatis, which can damage a woman’s reproductive organs such as the uterus, fallopian tube, ovaries etc
This study was conducted to estimate the seroprevalence of C. trachomatis infection among pregnant women attending antenatal clinics in Kaduna metropolis, North Central Nigeria, and to assess some of the risk factors associated with the disease
The qualitative immunoenzymatic determination of IgG - class antibodies against C. trachomatis is based on the Enzyme linked immunosorbent assay technique (ELISA)
Summary
Chlamydia is a common sexually transmitted disease caused by the bacterium Chlamydia trachomatis, which can damage a woman’s reproductive organs such as the uterus (womb), fallopian tube, ovaries etc. Perinatal infections occur; as many as half of all infants born to mothers with chlamydia will be born with the disease (Chojnacka et al, 2012). Chlamydia can affect infants causing spontaneous abortion, premature birth, conjunctivitis, which may lead to blindness, and pneumonia (Cates et al, 1990). Active young people are at high risk of acquiring chlamydia, due to a combination of behavioral, biological, and cultural reasons (Eaton et al, 2012). This study was conducted to estimate the seroprevalence of C. trachomatis infection among pregnant women attending antenatal clinics in Kaduna metropolis, North Central Nigeria, and to assess some of the risk factors associated with the disease
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