English

Abstract

IntroductionPantoea agglomerans (P. agglomerans) is gram negative bacterium that belongs to the family Enterobacteriaceae. It is an opportunistic pathogen in the immunocompromised, causing wound infections, bacteremia, and urinary tract infections. This species is currently listed as a Biosafety level 2 (BL2) organism due to clinical reports as an opportunistic human pathogen. Septic arthritis or synovitis is usually common, clinical manifestations caused by P. agglomerans and often correlated with a predisposing factor i.e. immunodeficiency (diabetes mellitus, malignancies, extremes of age) or use of central catheter. This is first described case of septic arthrit is following a road side injury. Case ReportIn May 2012, A 40 year old male was admitted to the hospital with pain in left leg since last three months and swelling in his left knee for 4 days which was insidious in onset. On physical examination he was a febrile. His left knee was warm, swollen and tender. Three days later he became febrile and swelling gradually progressed resulting in cellulites. Ampicillin and Gentamicin were initiated/ started empirically. Later on an ill defined ulcer with irregular margin developed associated with purulent discharge. Patient was diagnosed as septic arthritis. Arthrocentesis was done and aspiration of synovial fluid was sent for culture and sensitivity to microbiology department and culture growth was phenotypically identified as P. agglomerans. The final identification of the bacteria by the Vitec 2 Systems (bioMerieux, France) was P. agglomerans. with multidrug resistant pattern in in-vitro testing . Key wordsPantoea agglomerans, septic arthritis, extended spectrum β-lactamases International Journal of Microbiology Research ISSN: 0975-5276 & E-ISSN: 0975-9174, Volume 4, Issue 6, 2012 Introduction Pantoea agglomerans (P. agglomerans) is gram negative bacterium that belongs to the family Enterobacteriaceae. It is an opportunistic pathogen in the immunocompromised, causing wound infections, bacteremia, and urinary tract infections [1]. P. agglomerans, formerly named Enterobacter agglomerans is less often implicated in infection than Enterobacter aerogenes and Enterobacter cloacae and usually complicates debilitating illnesses. P. agglomerans strains are among the most promising biocontrol agents for a variety of bacterial and fungal plant diseases, particularly fire blight of apple and pear. This species is currently listed as a Biosafety level 2 (BL2) organism due to clinical reports as an opportunistic human pathogen [2-4]. Septic arthritis or synovitis is usually common, clinical manifestation caused by P. agglomerans and often correlated with a predisposing factor i.e. immunodeficiency (diabetes mellitus, malignancies, extremes of age) or use of central catheter [2-5]. This is first described case of septic arthritis following a road side injury in India. Case Report In May 2012, A 40 year old male was admitted to this hospital with pain in left leg since last three months and swelling in his left knee Citation: Mukesh Sharma, et al. (2012) Multidrug Resistant Pantoea agglomerans in a Patient with Septic Arthritis-a Rare Report from India. International Journal of Microbiology Research, ISSN: 0975-5276 & E-ISSN: 0975-9174, Volume 4, Issue 6, pp.-263-265. Copyright: Copyright©2012 Mukesh Sharma, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.