Abstract
BACKGROUND AND OBJECTIVES: Phrynoderma is a form of follicular hyperkeratosis that is associated with nutritional deficiencies. It is endemic to poor population and constitutes significant cases in dermatological clinics in India. The present study is undertaken to find out the therapeutic response in Phrynoderma cases. METHODS: A total of 100 patients with Phrynoderma after clinical diagnosis, who consented for study were included. Patients were divided into three groups of 34, 33 and 33 each. Following treatment regimens were given for each group. R1: Oral Vitamin A 50,000 IU daily for 8 weeks R2: Oral Vitamin E 100 IU daily for 8 weeks R3: Safflower Oil 1 tsp TD w/ meal for 1 month RESULTS: In a total of 100 patients of Phrynoderma studied; incidence was found to be 0.45% of which males were 63% and females were 37%. The male to female ratio was 1.70:1. Therapeutic response was better in R1 (Oral Vitamin A) group compared to R2 (Oral Vitamin E) group. Amongst R2 and R3 (safflower Oil), R2 showed better response compared to R3.
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