Abstract

Methanolic and chloroform extracts obtained from various parts of Schinus molle and Gleditsia triacanthos were evaluated by DPPH radical scavenging assay. The methanolic extracts from S. molle showed scavenging activity ranging from 35.97±1.02 to 83.38±2.74%, while the chloroform seed extract showed relatively weak scavenging activity ranging from 8.20±1.02 to 68.82±3.17%. The IC50 values of S. molle methanolic leaves extract, S. molle methanolic stem-bark extract and S. molle chloroform seed extract (SMMELS, SMMESB and SMCHSD) were found to be 476.43, 3000 µg mL-1, respectively. The positive controls, GAMEOH and GAETAC, showed an IC50 value <250 µg mL-1 each. From this study, we concluded that the extracts from these two medicinal plants, S. molle and G. triacanthos, showed promising antioxidant activity. Therefore, further investigations, such as bioactive guided isolation of pure compounds, antioxidant activity of pure compounds, application of these extracts or pure compounds in culinary, etc., are required. Key words: Antioxidant, chloroform extract, gallic acid, Schinus molle, Gleditsia triacanthos, radical scavenging assay, methanolic extract.

Highlights

  • The species Schinus molle L. known as American pepper, pervian pepper, pepper tree, aguaribay, peppercorn tree, etc., belongs to the Anarcardiaceae family (Mehani and Segni, 2013; Pedro et al, 2012; Trevor et al, 2013)

  • The methanolic stem-bark extract (SMMESB) from the present study showed a comparable IC50 value of

  • DPPH radical scavenging activity of methanolic and chloroform extracts obtained from various parts of two medicinal plants viz. S.molle and G. triacanthos collected from the Kingdom of Lesotho have been evaluated

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Summary

Introduction

The species Schinus molle L. known as American pepper, pervian pepper, pepper tree, aguaribay, peppercorn tree, etc., belongs to the Anarcardiaceae family (Mehani and Segni, 2013; Pedro et al, 2012; Trevor et al, 2013). S. molle is a medicinal plant used in traditional medicine (Abderrahim et al, 2018). The fruits (seeds) of S. molle are edible and they are about 5 mm diameter (Trevor et al, 2013). The seeds of S. molle are reddish pink and have a taste similar to pepper. It has been reported that S. molle has antibacterial, analgesic, cytotoxic, anti-inflammatory, antifungal, antiseptic, insecticidal, and antioxidant activities (Deveci et al, 2010; Diaz et al, 2008; Ferrero et al, 2006; Ruffa et al, 2002; Yueqin et al, 2003; Abir et al, 2016; Abderrahim et al, 2018; Bendaoud et al, 2010; Mohamed et al, 2016)

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