Abstract
The present investigation was carried out to study the effect of bromine on the biological activity of pyrazolines. Some previously synthesized substituted pyrazolines were brominated by bromine in acetic acid. The synthesized bromo-benzothiazolopyrazolines were characterized by elemental analysis, IR and PMR spectra. The synthesized bromo-benzothiazolopyrazolines were subjected to in-vitro antimicrobial activity against various pathogenic bacteria.
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