Abstract

In the ongoing phytochemical study, an effort was made to investigate cytotoxicity of various crude fractions of aerial parts of Indigofera heterantha. The results obtained revealed that all the fractions including n-hexane, ethyl acetate, methanol and residue showed brine shrimp (Artemia salina Leach) cytotoxicity activity. The data obtained revealed the medicinal importance of the plant and will help the researchers to exploit the phytochemicals for biological activities (cytotoxicity).   Key words: Indigofera heterantha, cytotoxicity, aerial parts.

Highlights

  • The genus Indigofera consists of about 700 species

  • The results obtained revealed that all the fractions including n-hexane, ethyl acetate, methanol and residue showed brine shrimp (Artemia salina Leach) cytotoxicity activity

  • The data obtained revealed the medicinal importance of the plant and will help the researchers to exploit the phytochemicals for biological activities

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Summary

Introduction

The genus Indigofera consists of about 700 species. Indigofera heterantha, commonly known as ghorega belongs to family leguminosae (Fabeaceae) (Hamayun et al, 2003). This plant is abundantly available in the northern regions of Pakistan. The species Indigofera pulchra has shown snake-venom neutralizing activity (Abubakar et al, 2006). The leaves and flowers of Indigofera aspalathoides have cooling effect and used to treat leprosy and cancerous diseases. The leaves of this plant are applied to abscesses and roots are used to treat dentifrice and mouth ulcers.

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