English

Abstract

Extramedullary plasmacytoma is a rare malignant plasma cell tumor. We report two extremely rare cases of extramedullary plasmacytoma, one of the maxillary sinus and the other of the nasal cavity. A 57 yr old man presented with swelling of right maxilla and hard palate. CT scan revealed right maxillary mass with inferior and lateral extension. Another 63 yr old woman presented with mass in left nostril with a huge swelling to the left of nose. Histopathology examination of both the masses revealed abundant plasma cells and diagnosed as extramedullary plasmacytoma. Both patients were planned for radiotherapy. INTRODUCTION: Extramedullary plasmacytoma is a localized collection of monoclonal plasma cells in an extra skeletal site. Extramedullary plasmacytoma (EMP) represents approximately 3% of all plasma cell neoplasms and < 1% of all head and neck tumors (1). The tumours arise predominantly in the sub mucosal tissues of the nasal cavity, paranasal sinus, nasopharynx, oropharynx and larynx. The nasal cavity and nasal septum are probably the most common locations.(2) The incidence in males is three times that of females. The most affected age group is 50–70 years. It is usually solitary or localized, but 10% of the patient have multiple site involvement.(3) We present two cases of extramedullary plasmacytoma. One of the right maxillary sinus and the other of the left nasal cavity.