Abstract
From the air dried aerial parts of Citrullus colocynthis, two new alkaloids namely, 2-(nonan-8-one)-(1H)-4-quinolone and 2-(Nonan-8-one) 4-methoxy-quinoline were isolated. Two flavonoids, (2S)-3\, 4\ -methylenedioxy -5, 7-dimethoxy flavan and hispidulin 7- (6 – E – β coumaroyl – β – D glucopyranoside) were also extracted and identified. The structures were established by conventional methods of analysis and confirmed by UV, IR, 1H and13CNMR, and mass spectra. Key words: Citrullus colocynthis, cucurbitaceae, new quinoline, quinolone alkaloids, flavonoids.
Highlights
Citrullus colocynthis (L.) is an important medicinal plant belonging to the family cucurbitaceae
The curative properties of medicinal plants are mainly due to the presence of various complex chemical substances of different composition which occur as secondary metabolites (Karthikeyan et al, 2009)
Several active chemical constituents of C. colocynthis plant were recorded. They are grouped as alkaloids, flavonoids, saponins, tannins, carbohydrates, glycosides and essential oils
Summary
Citrullus colocynthis (L.) is an important medicinal plant belonging to the family cucurbitaceae. From the air dried aerial parts of Citrullus colocynthis, two new alkaloids namely, 2-(nonan-8-one)-(1H)4-quinolone and 2-(Nonan-8-one) 4-methoxy-quinoline were isolated. Two flavonoids, (2S)-3\, 4\ methylenedioxy -5, 7-dimethoxy flavan and hispidulin 7- (6 – E – β coumaroyl – β – D glucopyranoside) were extracted and identified. Two new alkaloids (compounds 1 and 2) were isolated from the aerial parts of C. colocynthis.
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