English

Abstract

AIM: To determine the proportion of ocular abnormalities in renal transplant patients and to correlate them with the: Underlying cause of renal insufficiency. Post-transplant duration. Immune suppressive regimens. MATERIALS AND METHODS: This cross sectional study was performed on 100 patients in M S Ramaiah Hospital between Nov 2010 to May 2012 who had received a renal transplant of at least 3 months duration with serum creatinine levels <3 mg/dl. All patients underwent a complete ophthalmologic examination. Clinical variables related to the transplant included cause of renal failure, duration of renal transplantation and immunosuppressive regimen. RESULTS: Overall, 83 male and 17 female patients with mean age of 43.22 ± 9.34 years were included. Ocular abnormality could be detected in 65%. The most common primary etiology of renal failure in patients was DM Nephropathy found in 37 (37%). Visual acuity < 6/9 seen in 48%, Conjunctival degenerative changes is seen in 24%, Cataractous changes mainly PSC seen in 34%, Clinically Significant Macular Edema (CSME) was seen in 4%, Central Serous Retinopathy changes seen in 3%, Hypertensive Retinopathy changes seen in 15%, Branch Retinal Vein Occlusion (BRVO) was seen in 4%, Mild NPDR changes was seen in 6%, Moderate NPDR changes was seen in 11%. Severe NPDR changes were seen in 15%, Proliferative Diabetic Retinopathy (PDR) changes was seen in 11%, Ocular HTN seen in 2%. Abnormal ocular findings were not correlated with the renal disorder or use of post-transplant immunosuppressive regimen but correlated with post-transplant duration. CONCLUSION: All patients undergoing renal transplant at should undergo complete ocular examination post renal transplantation for early detection, better management of ophthalmic complications for good visual outcome and improved quality of life.