Abstract

This study aimed at assessing the reactive thrombocytosis and erythrocyte sedimentation rate in patients with pulmonary tuberculosis living in Port Sudan City, Red Sea State, Sudan. This study covers the period from June 2006 up to December 2008 at Port Sudan Tuberculosis Diagnostic Center. Hundred newly discovered Ziehl Neelsen stain positive males (77%) and females (23%) were randomly selected to be the study sample and fifty apparently healthy adult males (76%) and females (24%) were also randomly selected to be the control group of the study. The ages of the patients ranged from 14 to 70 years old. Thrombocytosis was detected in 20% of the patients. The erythrocyte sedimentation rate (ESR) was increased in 100% of the patients. The changes in these parameters (platelets count and ESR) may reflect a reaction to the inflammatory condition. Therefore, in endemic areas, the presence of such hematological peripheral blood changes may raise the suspicion of pulmonary tuberculosis. Key words: Tuberculosis, thrombocytosis, erythrocyte sedimentation rate (ESR), Port Sudan.

Highlights

  • Tuberculosis (TB) is a major public health problem in Port Sudan, Sudan (Ageep, 2012)

  • Reactive thrombocytosis is defined as an increased number of platelets above 450×109 L-1 due to a reaction to a stimulus e.g. an inflammatory condition

  • Descriptive statistics were used for analysis (e.g, t test, pie chart). This is a case control-analytical study conducted in Port Sudan Tuberculosis Diagnostic center

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Summary

Introduction

Tuberculosis (TB) is a major public health problem in Port Sudan, Sudan (Ageep, 2012). The pulmonary type is the most important form of tuberculosis, continues to be one of the most wide spread infectious diseases (World health Organization, 2001). Hematological changes associated with pulmonary TB infection have been the first documented study in Red Sea State (Ageep, 2012). Reactive thrombocytosis is defined as an increased number of platelets above 450×109 L-1 due to a reaction to a stimulus e.g. an inflammatory condition.

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