English

Abstract

Worldwide extensive use of agrochemicals in agricultural production poses potential ecotoxicological effects and disturbs aquatic biota, more specially fish. This study aims to evaluate comparative effects of selected agrochemicals such as profenofos, endosulfan and deltamethrin on biochemical, endocrine and genetic profiles of the common carp (Cyprinus carpio L.). Forty healthy carp (50 ± 7.45g and 15 ± 5.86 cm) were selected randomly and equally divided into four groups; control group labeled as E0 and three treated groups having 4 ppb of profenofos, deltamethrin and endosulfan, labeled as E1, E2, E3 respectively. Fish were exposed to chemicals for 96 h. Obtained results revealed that, significant changes were observed in biochemical parameters of treated groups in comparison with control group (P < 0.05): glucose, creatinine, serum amylase, alkaline phosphate, sodium and phosphorus levels increased significantly, while a significant (P < 0.05) reduction was recorded in serum protein, triglycerides, serum lipase and magnesium levels. Whereas significant increase in TSH and cortisol levels were found, while significant decrease (P < 0.05) in T3, T4 and insulin level were observed in experimental groups as compared to control group. Genetic parameters were also affected under the stressors and showed significant increase (P < 0.05) in micronuclei frequency in erythrocytes of treated fish compared to the control group. Toxicities of the three agrochemicals were: endosulfan > deltamethrin > profenofos. The obtained results provide solid evidence that unobservant use of such agrochemical causes a pernicious effect on nontarget organisms such as fish. © 2021 Friends Science Publishers